The common autoimmune disease type 1 diabetes provides a paradigm for the genetic analysis of multifactorial disease. Disease occurrence is attributable to the interaction with the environment of alleles at many loci interspersed throughout the genome. Their mapping and identification is difficult because the disease-associated alleles occur almost as commonly in patients as in healthy individuals; even the highest-risk genotypes bestow only modest risks of disease. The identification of common quantitative trait loci (QTL) in autoimmune disease and in other common (...) disorders, therefore,requires a very close marriage of genetics and biology. Two QTLs have been identified in human type 1 diabetes: the major histocompatibility complex HLA class II loci and a promoter polymorphism of the insulin gene. The evidence for their primary roles in disease aetiology demonstrates the necessity of combined studies of genetics and biology. Their functions and interaction underpin an emerging picture of the basic causes of the disease and direct analyses towards other candidate genes and pathways. The genetic tools used for QTL identification include transgenesis and gene knockouts, whole genome scanning for linkage, mouse congenic strains, linkage disequilibrium mapping, and the establishment of ancestral haplotypes among disease-associated chromosomes. BioEssays 1999;21:164–174. © 1999 John Wiley & Sons, Inc. (shrink)

In his recent essay in the Philosophical Review, “Truth and Freedom,” Trenton Merricks contends (among other things) that the basic argument for the incompatibility of God's foreknowledge and human freedom is question-begging. He relies on a “truism” to the effect that truth depends on the world and not the other way around. The present essay argues that mere invocation of this truism does not establish that the basic argument for incompatibilism is question-begging. Further, it seeks to clarify important elements of (...) the debate, including the fixity-of-the-past premise in the incompatibilist's argument and the Ockhamist response. It sketches some potential links between the issues here and recent work on ontological dependence, and it connects the issues raised by Merricks to important work that has appeared in (among other places) the Philosophical Review. (shrink)

We typically think we have free will. But how could we have free will, if for anything we do, it was already true in the distant past that we would do that thing? Or how could we have free will, if God already knows in advance all the details of our lives? Such issues raise the specter of "fatalism". This book collects sixteen previously published articles on fatalism, truths about the future, and the relationship between divine foreknowledge and human freedom, (...) and includes a substantial new introductory essay and bibliography. Many of the pieces collected here build bridges between discussions of human freedom and recent developments in other areas of metaphysics, such as philosophy of time and the nature of metaphysical "dependence". Ideal for courses in free will, metaphysics, and philosophy of religion, Freedom, Fatalism, and Foreknowledge will encourage important new directions in thinking about free will, time, and truth. (shrink)

Humans and many other species selectively attend to stimuli or stimulus dimensions—but why should an animal constrain information input in this way? To investigate the adaptive functions of attention, we used a genetic algorithm to evolve simple connectionist networks that had to make categorization decisions in a variety of environmental structures. The results of these simulations show that while learned attention is not universally adaptive, its benefit is not restricted to the reduction of input complexity in order to keep it (...) within an organism's processing capacity limitations. Instead, being able to shift attention provides adaptive benefit by allowing faster learning with fewer errors in a range of ecologically plausible environments. (shrink)

Although successive generations of digital technology have become increasingly powerful in the past 20 years, digital democracy has yet to realize its potential for deliberative transformation. The undemocratic exploitation of massive social media systems continued this trend, but it only worsened an existing problem of modern democracies, which were already struggling to develop deliberative infrastructure independent of digital technologies. There have been many creative conceptions of civic tech, but implementation has lagged behind innovation. This article argues for implementing one such (...) vision of digital democracy through the establishment of a public corporation. Modeled on the Corporation for Public Broadcasting in the United States, this entity would foster the creation of new digital technology by providing a stable source of funding to nonprofit technologists, interest groups, civic organizations, government, researchers, private companies, and the public. Funded entities would produce and maintain software infrastructure for public benefit. The concluding sections identify what circumstances might create and sustain such an entity. (shrink)

Numerous experiments have examined whether moving stimuli capture spatial attention but none have sought to determine whether visual features of looming and receding objects are extracted in a capacity-free manner. The current experiment used the task-choice procedure originated by Besner and Care to examine this possibility. Stimuli were presented in 3D space by manipulating retinal disparity. Results indicate that features of an object are extracted in a capacity-free manner for both looming and receding objects for participants who consciously perceive motion (...) but not for participants who do not consciously perceive motion. These results suggest that the cognitive system is biased to process potentially animate objects, perhaps because of the evolutionary advantage this cognitive ability may provide. (shrink)

Is time travel just a confusing plot device deployed by science fiction authors and Hollywood filmmakers to amaze and amuse? Or might empirical data prompt a scientific hypothesis of time travel? Structured on a fascinating dialogue involving  ...

Physical activity, and likely the motivation for it, varies throughout the day. The aim of this investigation was to create a short assessment (CRAVE: Cravings for Rest and Volitional Energy Expenditure) to measure motivation states (wants, desires, urges) for physical activity and sedentary behaviors. Five studies were conducted to develop and evaluate the construct validity and reliability of the scale, with 1,035 participants completing the scale a total of 1,697 times. In Study 1, 402 university students completed a questionnaire inquiring (...) about the want or desire to perform behaviors “at the present moment (right now).” Items related to physical activity (e.g., “move my body”) and sedentary behaviors (e.g., “do nothing active”). An exploratory structural equation model (ESEM) revealed that 10 items should be retained, loading onto two factors (5 each for Move and Rest). In Study 2, an independent sample (n= 444) confirmed these results and found that Move and Rest desires were associated with stage-of-change for exercise behavior. In Study 3, 127 community-residing participants completed the CRAVE at 6-month intervals over two years- two times each session. Across-session interclass correlations (ICC) for Move (ICC = 0.72–0.95) and Rest (ICC = 0.69–0.88) were higher than when they were measured across 24-months (Move: ICC = 0.53; Rest: ICC = 0.49), indicating wants/desires have state-like qualities. In Study 4, a maximal treadmill test was completed by 21 university students. The CRAVE was completed immediately pre and post. Move desires decreased 26% and Rest increased 74%. Changes in Move and Rest desires were moderately associated with changes in perceived physical fatigue and energy. In Study 5, 41 university students sat quietly during a 50-min lecture. They completed the CRAVE at 3 time points. Move increased 19.6% and Rest decreased 16.7%. Small correlations were detected between move and both perceived energy and tiredness, but not calmness or tension. In conclusion, the CRAVE scale has good psychometric properties. These data also support tenets of the WANT model of motivation states for movement and rest (Stults-Kolehmainen et al., 2020a). Future studies need to explore how desires to move/rest relate to dynamic changes in physical activity and sedentarism. (shrink)

Parents respond to the death of a child in very different ways. Some parents may be violent or angry, some sad and tearful, some quiet and withdrawn, and some frankly delusional. We present a case in which a father’s reaction to his daughter’s death is a desire to protect his wife from the stressful information. The wife is in the second trimester of a high-risk pregnancy and so is particularly fragile. We asked pediatricians and bioethicists to discuss the ways in (...) which they might respond to the father’s understandable but troubling request. -/- The death of a young child is one of the most stressful events that can happen to parents. The stress of such a loss is compounded if the parents are in a foreign country, far from home, and without a network of family and friends to provide social support. The stress may be more difficult to deal with if the parents have acute health problems of their own. In this month’s “Ethics Rounds,” we present a case in which a father whose daughter died requested that the doctors delay telling his wife. His reason: She is pregnant, in the second trimester, and on bed rest because of preterm labor. He does not want to add to her stress. We asked both pediatricians and bioethicists to respond to this request. (shrink)

PurposeTo use the power of knowledge acquisition and machine learning in the development of a collaborative computer classification system based on the features of age-related macular degeneration (AMD).MethodsA vocabulary was acquired from four AMD experts who examined 100 ophthalmoscopic images. The vocabulary was analyzed, hierarchically structured, and incorporated into a collaborative computer classification system called IDOCS. Using this system, three of the experts examined images from a second set of digital images compiled from more than 1000 patients with AMD. Images (...) were annotated, and features were identified and defined. Decision trees, a machine learning method, were trained on the data collected and used to extract patterns. Interrelationships between the data from the different clinicians were investigated.ResultsSix drusen classes in the structured vocabulary were largely sufficient to describe all the identified features. The decision trees classified the data with 76.86% to 88.5% accuracy and distilled patterns in the form of hierarchical trees composed of 5 to 15 nodes. Experts were largely consistent in their characterization of soft, and to a lesser extent, hard drusen, but diverge in definition of other drusen. Size and crystalline morphology were the main determinants of drusen type across all experts.ConclusionsMachine learning is a powerful tool for the characterization of disease phenotypes. The creation of a defined feature set for AMD will facilitate the development of an IDOCS-based classification system. (shrink)

This Introduction has three sections, on "logical fatalism," "theological fatalism," and the problem of future contingents, respectively. In the first two sections, we focus on the crucial idea of "dependence" and the role it plays it fatalistic arguments. Arguably, the primary response to the problems of logical and theological fatalism invokes the claim that the relevant past truths or divine beliefs depend on what we do, and therefore needn't be held fixed when evaluating what we can do. We call the (...) sort of dependence needed for this response to be successful "dependence with a capital 'd'": Dependence. We consider different accounts of Dependence, especially the account implicit in the so-called "Ockhamist" response to the fatalistic arguments. Finally, we present the problem of future contingents: what could "ground" truths about the undetermined future? On the other hand, how could all such propositions fail to be true? (shrink)

Previous research demonstrates that consumers support firms’ CSR activities, and increasingly demand socially responsible products and services. However, an implicit assumption in the extant literature is that the purchaser and the consumer of the product are the same person. The current research focuses on a unique form of socially responsible consumption behavior: gift-giving. Through 30 depth consumer interviews, we develop a typology of consumers based on whether consumers integrate CSR-related information into purchases, and whether the purchases are for themselves or (...) for others. We find that in some instances, consumers actively avoid purchasing products from socially responsible organizations and do so with the intention of managing their impressions with the gift recipient. This is counter to previous research that suggests consumers often choose to make socially responsible consumption decisions in efforts to satisfy self-presentation concerns. In addition, the decision to engage in socially responsible consumption for oneself but not for others was motivated by a variety of factors including the role of the recipient and a concern over the credibility of socially responsible gifts. Finally, some participants who do not incorporate CSR into their own personal consumption chose gifts based on a variety of CSR activities in an effort to build awareness for socially responsible organizations. (shrink)

In this paper we critically evaluate Trenton Merricks’s recent attempt to provide a “new” way of defending compatibilism about divine foreknowledge and human freedom. We take issue with Merricks’s claim that his approach is fundamentally different from Ockhamism. We also seek to highlight the implausibility of Merricks’s rejection of the assumption of the fixity of the past, and we also develop a critique of the Merricks’s crucial notion of “dependence.”.

This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1799 edition. Excerpt:... chapter viii. discipline' of the heart. One of the first steps to be taken, if you would have a character that will stand by you in prosperity and in adversity, in life and death, is to fortify your mind, with fixed principles. There is no period of (...) life in which the heart is so much inclined to scepticism and infidelity as in youth. Not that young men are infidels, but the mind is tossed from doubt to doubt, like a light boat leaping from wave to wave. There is no positive settling down into deism or infidelity, but the heart is full of doubting, so that the mind has no position, in morals or religion, fortified. If the restraints of education are so far thrown off as to allow you to indulge in sin, Which is in any way disgraceful if known, you will then easily become an infidel. "The nurse of infidelity is sensuality. The young are sensual. The Bible stands in their way. It prohibits the indulgence of ' the lust of the flesh, the lust of the eye, and the pride of life.' But the young mind loves these things, and therefore it hates the Bible, which prohibits them. It is prepared to say, ' If any man will bring me arguments against the Bible, I will thank him; if not, I will invent them.' As to infidel arguments, there is no weight in them. They are jejune and refuted. Infidela are not themselves convinced by them. What sort of men are infidels? They are loose, fierce, overbearing men. There is nothing in them like sober and serious inquiry. They are the wildest fanatics on earth. Nor have they agreed among themselves on any scheme of truth and felicity. Look at the needs and necessities of man. 'Every pang of grief tells a man he needs a helper; but infidelity provides none. And what can its schemes do for you in death?' Examine your... (shrink)

In Roman Catholic moral theology there is an ongoing debate between the proportionalist or revisionist school and the traditionalist school that has developed what is referred to as the ‘New Natural Law Theory’ or ‘Basic Goods Theory’ . The stakes in this debate have been raised with Pope John Paul II's encyclical Veritatis Splendor on fundamental moral theology that condemned ‘proportionalism’ or ‘teleologism’ as an ethical theory while utilizing many of the ideas, concepts, and terminology of the BGT, thereby (...) implicitly endorsing that ethical theory. While absolute norms and intrinsically evil acts have frequently been the focus of debate between these two schools, what is it that divides them fundamentally, on the level of ethical method? It is the role and function of reason and experience as two sources of moral knowledge, in part, that distinguish these two versions of natural law on the most basic level. While the BGT has a strict hierarchy of the sources of moral knowledge that posits the hierarchical magisterium as the definitive interpreter of reason and experience, revisionists posit a more dialogical relationship between reason, experience, and the magisterium. On certain ethical issues , the experience of the faithful as well as the rational arguments developed by revisionist Catholic moral theologians challenge some of the normative claims of the magisterium. This paper investigates the methodological use of reason and experience in each theory's interpretation of natural law and how and why these two sources of moral knowledge lead to fundamentally divergent normative claims on particular ethical issues. (shrink)

The consideration of normative ethics and methodology is a relatively recent phenomena in Catholic moral theology. Similar to any nascent discussion, having adopted terms and concepts from one conceptual genre, Britisch-analytic philosophy, into a radically other genre, Catholic moral theology, one then needs to begin the work of clarifying how, and to what extent, those terms and concepts contribute to the overall project of moral theology as a science. As Pope John Paul II's encyclical Veritatis Splendor attests, this incorporation (...) has met with a great deal of resistance based on misunderstandings of the nature and purpose of normative ethics and methodology. Deontology and Teleology is a pioneer account which exposes and clarifies many of the terminological and conceptual ambiguities inherent to this discussion. It begins with an investigation of C.D. Broad's meta-ethical division of theories into deontology and teleology, and the epistemological/ontological foundations on which he established this division. An analysis of how and why Broad's theory has been incorporated into Catholic discussions on the foundation and formulation of norms along with the inherent difficulties of such an incorporation is then taken up. Finally, this study argues and substantiates through detailed historical analysis that a fundamental difference between traditionalists and revisionists in their relative perspectives on norms rest in the traditional understanding and moral evaluation of the human act, specifically, the objectum, circumstantiae and finis (fontes moralitates). This is an indispensable resource work for those interested in fundamental moral theology and lays the foundation for pursuing further the complex question of normative ethics in Catholic moral theology. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Animals depleting one patch of resources must decide when to leave and switch to a fresh patch. Foraging theory has predicted various decision mechanisms; which is best depends on environmental variation in patch quality. Previously we tested whether these mechanisms underlie human decision making when foraging for external resources; here we test whether humans behave similarly in a cognitive task seeking internally generated solutions. Subjects searched for meaningful words made from random letter sequences, and as their success rate declined, they (...) could opt to switch to a fresh sequence. As in the external foraging context, time since the previous success and the interval preceding it had a major influence on when subjects switched. Subjects also used the commonness of sequence letters as a proximal cue to patch quality that influenced when to switch. Contrary to optimality predictions, switching decisions were independent of whether sequences differed little or widely in quality. (shrink)

Archer's argument regarding sex differences in partner violence rests on a general account of between-sex differences in reproductive strategies and in social roles. However, men's partner-directed violence often is predicted by perceived risk of female infidelity. We hypothesize that men's partner-directed violence is produced by psychological mechanisms evolved to solve the adaptive problem of paternity uncertainty.

Pope John Paul II called for an intense dialogue between science and theology, “a common interactive relationship,” in which each discipline is “open to the discoveries and insights of the other” while retaining its own integrity. This essay seeks to be responsive to that call and is an initial exploration of relationships between contemporary neuroscience and Catholic theological ethics. It examines neuroscientific data on the bicameral brain and theological ethical data on marital ethics, including divorce and remarriage, and asks (...) what insight the former might provide into both the latter and the different ethical methods that respond to marital ethics. The analysis is undertaken in the hope of illuminating a pathway that opens the insights of one way of doing theological ethics to the insights of another way, thereby eliminating the unnecessary, unhelpful, and sometimes un‐Christian polarizations that presently separate them. (shrink)

Connexins were first identified in the 1970s as the molecular components of vertebrate gap junctions. Since then a large literature has accumulated on the cell and molecular biology of this multi‐gene family culminating recently in the findings that connexin mutations are implicated in a variety of human diseases. Over two decades, the terms “connexin” and “gap junction” had become almost synonymous. In the last few years a second family of gap‐junction genes, the innexins, has emerged. These have been shown to (...) form intercellular channels in genetically tractable invertebrate organisms such as Drosophila melanogaster and Caenorhabditis elegans. The completed genomic sequences for the fly and worm allow identification of the full complement of innexin genes in these two organisms and provide valuable resources for genetic analyses of gap junction function. BioEssays 23:388–396, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

There is fierce controversy in the United States over whether parents should be able to choose their children's schools and/or curriculum. To discuss the pedagogical arguments inherent in this question, Todd Alan Price and Ruprecht Mattig begin with the classical concept of Bildung as developed by Wilhelm von Humboldt around 1800. Next, they compare Humboldt's ideas with the ideas of John Stuart Mill and Milton Friedman, who stand in the tradition of liberal thought, as Mill was strongly influenced (...) by Humboldt and Friedman, in turn, by Mill. Finally, they consider Friedman's role as a central figure in the school choice movement, and are thus able to trace a line of thought from Humboldt to actual controversies. Price and Mattig's analysis here shows that the liberalism of Humboldt, Mill, and Friedman revolves around diversity and choice in education. Moreover, it traces that in the process of translating, translocating, and transcontextualizing Humboldt's original thought through Mill to Friedman, the complexity of arguments about education and the role of parents and the state in a liberal society has been unduly reduced. The authors conclude the paper by proposing a principle for thinking about the relationship between different educational institutions in democracies. (shrink)

This article explores the significance that environments play in terms of the learning process. In the United States, the legacy of John Dewey's intellectual efforts left a theoretical understanding that views the architectural composition of learning environments as instrumental mediums which house the educational process. This understanding of learning environments is precipitated by a separation of human agents as subjects and their environments as objects. By contrast, Martin Heidegger's theory of ontology, and its reconfiguration of the subject and object (...) relationship, lends itself to an understanding of the architectural composition of learning environments as dwellings. (shrink)

Can new technology enhance purpose-driven, democratic dialogue in groups, governments, and societies? Online Deliberation: Design, Research, and Practice is the first book that attempts to sample the full range of work on online deliberation, forging new connections between academic research, technology designers, and practitioners. Since some of the most exciting innovations have occurred outside of traditional institutions, and those involved have often worked in relative isolation from each other, work in this growing field has often failed to reflect the full (...) set of perspectives on online deliberation. This volume is aimed at those working at the crossroads of information/communication technology and social science, and documents early findings in, and perspectives on, this new field by many of its pioneers. -/- CONTENTS: -/- Introduction: The Blossoming Field of Online Deliberation (Todd Davies, pp. 1-19) -/- Part I - Prospects for Online Civic Engagement -/- Chapter 1: Virtual Public Consultation: Prospects for Internet Deliberative Democracy (James S. Fishkin, pp. 23-35) -/- Chapter 2: Citizens Deliberating Online: Theory and Some Evidence (Vincent Price, pp. 37-58) -/- Chapter 3: Can Online Deliberation Improve Politics? Scientific Foundations for Success (Arthur Lupia, pp. 59-69) -/- Chapter 4: Deliberative Democracy, Online Discussion, and Project PICOLA (Public Informed Citizen Online Assembly) (Robert Cavalier with Miso Kim and Zachary Sam Zaiss, pp. 71-79) -/- Part II - Online Dialogue in the Wild -/- Chapter 5: Friends, Foes, and Fringe: Norms and Structure in Political Discussion Networks (John Kelly, Danyel Fisher, and Marc Smith, pp. 83-93) -/- Chapter 6: Searching the Net for Differences of Opinion (Warren Sack, John Kelly, and Michael Dale, pp. 95-104) -/- Chapter 7: Happy Accidents: Deliberation and Online Exposure to Opposing Views (Azi Lev-On and Bernard Manin, pp. 105-122) -/- Chapter 8: Rethinking Local Conversations on the Web (Sameer Ahuja, Manuel Pérez-Quiñones, and Andrea Kavanaugh, pp. 123-129) -/- Part III - Online Public Consultation -/- Chapter 9: Deliberation in E-Rulemaking? The Problem of Mass Participation (David Schlosberg, Steve Zavestoski, and Stuart Shulman, pp. 133-148) -/- Chapter 10: Turning GOLD into EPG: Lessons from Low-Tech Democratic Experimentalism for Electronic Rulemaking and Other Ventures in Cyberdemocracy (Peter M. Shane, pp. 149-162) -/- Chapter 11: Baudrillard and the Virtual Cow: Simulation Games and Citizen Participation (Hélène Michel and Dominique Kreziak, pp. 163-166) -/- Chapter 12: Using Web-Based Group Support Systems to Enhance Procedural Fairness in Administrative Decision Making in South Africa (Hossana Twinomurinzi and Jackie Phahlamohlaka, pp. 167-169) -/- Chapter 13: Citizen Participation Is Critical: An Example from Sweden (Tomas Ohlin, pp. 171-173) -/- Part IV - Online Deliberation in Organizations -/- Chapter 14: Online Deliberation in the Government of Canada: Organizing the Back Office (Elisabeth Richard, pp. 177-191) -/- Chapter 15: Political Action and Organization Building: An Internet-Based Engagement Model (Mark Cooper, pp. 193-202) -/- Chapter 16: Wiki Collaboration Within Political Parties: Benefits and Challenges (Kate Raynes-Goldie and David Fono, pp. 203-205) -/- Chapter 17: Debian’s Democracy (Gunnar Ristroph, pp. 207-211) -/- Chapter 18: Software Support for Face-to-Face Parliamentary Procedure (Dana Dahlstrom and Bayle Shanks, pp. 213-220) -/- Part V - Online Facilitation -/- Chapter 19: Deliberation on the Net: Lessons from a Field Experiment (June Woong Rhee and Eun-mee Kim, pp. 223-232) -/- Chapter 20: The Role of the Moderator: Problems and Possibilities for Government-Run Online Discussion Forums (Scott Wright, pp. 233-242) -/- Chapter 21: Silencing the Clatter: Removing Anonymity from a Corporate Online Community (Gilly Leshed, pp. 243-251) -/- Chapter 22: Facilitation and Inclusive Deliberation (Matthias Trénel, pp. 253-257) -/- Chapter 23: Rethinking the ‘Informed’ Participant: Precautions and Recommendations for the Design of Online Deliberation (Kevin S. Ramsey and Matthew W. Wilson, pp. 259-267) -/- Chapter 24: PerlNomic: Rule Making and Enforcement in Digital Shared Spaces (Mark E. Phair and Adam Bliss, pp. 269-271) -/- Part VI - Design of Deliberation Tools -/- Chapter 25: An Online Environment for Democratic Deliberation: Motivations, Principles, and Design (Todd Davies, Brendan O’Connor, Alex Cochran, Jonathan J. Effrat, Andrew Parker, Benjamin Newman, and Aaron Tam, pp. 275-292) -/- Chapter 26: Online Civic Deliberation with E-Liberate (Douglas Schuler, pp. 293-302) -/- Chapter 27: Parliament: A Module for Parliamentary Procedure Software (Bayle Shanks and Dana Dahlstrom, pp. 303-307) -/- Chapter 28: Decision Structure: A New Approach to Three Problems in Deliberation (Raymond J. Pingree, pp. 309-316) -/- Chapter 29: Design Requirements of Argument Mapping Software for Teaching Deliberation (Matthew W. Easterday, Jordan S. Kanarek, and Maralee Harrell, pp. 317-323) -/- Chapter 30: Email-Embedded Voting with eVote/Clerk (Marilyn Davis, pp. 325-327) -/- Epilogue: Understanding Diversity in the Field of Online Deliberation (Seeta Peña Gangadharan, pp. 329-358). -/- For individual chapter downloads, go to odbook.stanford.edu. (shrink)

Cancer and its treatment pose challenges that affect not only patients but also their significant others, including intimate partners. Accumulating evidence suggests that couples’ ability to communicate effectively plays a major role in the psychological adjustment of both individuals and the quality of their relationship. Two key conceptual models have been proposed to account for how couple communication impacts psychological and relationship adjustment: the social-cognitive processing (SCP) model and the relationship intimacy (RI) model. These models posit different mechanisms and outcomes, (...) and thus have different implications for intervention. The purpose of this project is to test and compare the utility of these models using comprehensive and methodologically rigorous methods. Aims are: (1) to examine the overall fit of the SCP and RI models in explaining patient and partner psychological and relationship adjustment as they occur on a day-to-day basis and over the course of 1 year; (2) to examine the fit of the models for different subgroups (males vs. females, and patients vs. partners); and (3) to examine the utility of various methods of assessing communication by examining the degree to which baseline indices from different measurement strategies predict self-reported adjustment at 1-year follow up. The study employs a longitudinal, multi-method approach to examining communication processes including: standard self-report questionnaires assessing process and outcome variables collected quarterly over the course of 1 year; smartphone-based ecological momentary assessments to sample participant reports in real time; and laboratory-based couple conversations from which we derive observational measures of communicative behavior and affective expression, as well as vocal indices of emotional arousal. Participants are patients with stage II-IV breast, colon, rectal, or lung cancer and their spouses/partners, recruited from two NCI-designated comprehensive cancer centers. Results will be published in scientific journals, presented at scientific conferences, and conveyed to a larger audience through infographics and social media outlets. Findings will inform theory, measurement, and the design and implementation of efficacious interventions aimed at optimizing both patient and partner well-being. (shrink)

This essay describes not only the evolving identity of Newman’s The Idea of a University, but also the way in which this process points to a larger tension between what Augustine referred to as the City of God and the city of this world.While no other work is perhaps more quoted than Newman’s Idea in relation to theoretical conceptions of university life, the origins of this work are often little understood. As a result, Newman’s Idea frequently goes from being a (...) work whose identity is derived from the City of God to being a book whose identity is derived from various manifestations of the city of this world. (shrink)

In this new contribution to moral theory, Todd Lekan argues for a pragmatist conception of morality as an evolving, educational, and fallible practice of everyday life. Drawing on the work of John Dewey, Lekan asserts that moral norms are neither timeless truths nor subjective whims, but habits transmitted through practices. Like the habits that make up medicine or engineering, moral habits are subject to rational evaluation and change according to new challenges and circumstances.

Unnamed sources have claimed that Michael Novak is "credited with considerable input" into John Paul II's encyclical, Centesimus annus, such that the former's thought "is said to be reflected in" the document. However, while John Paul II affirms economic rights, Novak rejects them. In addition, the Pope critiques the gap between rich and poor and the consumerism that drives it; Novak finds them to be morally irrelevant. Following Catholic teaching before him, John Paul places restrictions on the (...) accumulation of private property for one's own use, while Novak identifies no such limits. Finally, while the Pope rejects the affirmation of any one system as a form of "ideology," Novak argues, "We are all capitalists now, even the Pope." Such dramatic differences suggest that the claim that Novak has influenced John Paul's thought is unfounded and that the former's position may even be one of dissent. (shrink)

In this article, I argue that political philosophers like Rawls and Habermas that characterize their methods as non-metaphysical or postmetaphysical depend on constitutions in order to provide a positive and public reference point for democratic participants. Michelman shows how this dependency is problematic, by contending that disagreement about the meaning of constitutional rights and the indeterminacy of their application undermines the rationality of consensus. I argue that his concerns raise serious problems for Rawls’ theory. Habermas, on the other hand, has (...) some tools to deal with Michelman’s critique — namely, his distinction between discourses of justification and application, and his idea of constitutional patriotism — but he must concede that much of the substance of constitutional democracy is basically up for grabs. I conclude by suggesting why these consequences are less threatening than they may seem. (shrink)

Efforts to retrieve John Courtney Murray's thought must address two questions: What has changed in the quarter-century since Murray's death? What resources does his oeuvre offer for the present situation? In examining Murray's contribution to current policy debates about church-state relations, I will first review the historically conscious methodology he drew upon and the details of his argument in favor of religious liberty. However, in the years since Murray wrote, American religious communities have been severely eroded, with the consequence (...) that Murray's argument no longer has the same force. I therefore propose a reformulation of the basis for religious freedom in order to take into account the need to maintain the social conditions necessary for the exercise of religious freedom. Such a reformulation has significant implications with regard to the question of public funding for religiously affiliated private schools. (shrink)

In August 2006, after twenty years of armed conflict, the Ugandan government and the rebel Lord’s Resistance Army came to a ceasefire agreement. While the LRA has moved its activity into neighboring countries, there has been peace—or at least the absence of overt conflict—in Uganda. The ecumenical Acholi Religious Leaders Peace Initiative was critical in mediating between the two parties in the months leading up to the talks. Archbishop John Baptist Odama has been Chairperson of ARLPI since 2002. Previous (...) interviews with him have been short and focused on only his external actions—the negotiations with the LRA, the acts of solidarity with displaced people, children in particular. In the present interview, however, Archbishop Odama discusses the spiritual formation, the devotional practices, and the deep theology that inform his actions on behalf of peace and justice. (shrink)

This book examines the political perspective of French thinker and historian Jacques Ranci&ère. Ranci&ère argues that a democratic politics emerges out of people&’s acting under the presupposition of their own equality with those better situated in the social hierarchy. Todd May examines and extends this presupposition, offering a normative framework for understanding it, placing it in the current political context, and showing how it challenges traditional political philosophy and opens up neglected political paths. He demonstrates that the presupposition of (...) equality orients political action around those who act on their own behalf&—and those who act in solidarity with them&—rather than, as with the political theories of John Rawls, Robert Nozick, and Amartya Sen, those who distribute the social goods. As May argues, Ranci&ère&’s view offers both hope and perspective for those who seek to think about and engage in progressive political action. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Spirit-Driven Leader: Seven Keys to Succeeding under Pressure by Carnegie Samuel CalianTodd V. CioffThe Spirit-Driven Leader: Seven Keys to Succeeding under Pressure by Carnegie Samuel Calian Louisville, KY: Westminster John Knox Press, 2010. 125pp. $15.00Great leadership is indispensable to the success of any organization, yet it so often seems in short supply. Carnegie Samuel Calian, former president of Pittsburgh Theological Seminary for more than twenty-five years, (...) seeks to remedy the latter by providing insight into the former. Drawn from his years of experience as a successful leader and based on rigorous research on the subject, [End Page 198] Calian’s helpful volume on leadership should prove valuable for current and potential leaders from all sectors of life. Although this work contains multiple references to biblical texts, theological claims, and pietistic practices, Calian does not limit himself to religious references but draws upon what he deems are, as we often say today, the “best practices” of leadership.Each chapter proceeds by identifying a great leader or leaders (in Calian’s mind), and each example is examined with regard to the questions of what makes this person a great leader and what lessons can be drawn from such a person. Calian’s choice of examples is wide ranging, moving from obvious ones—such as Jim Sinegal (CEO of Costco), Wendy Kopp (founder of Teach for America), Asma Jahangir (a Pakistani lawyer and human rights advocate), and Martin Luther King Jr.—to less obvious ones, such as anecdotal references to Calian’s mother, a childhood pastor, and so forth. In the end, Calian is not satisfied simply to construct a “theory” of leadership; rather, he contends, we must look for approaches to leadership that have been tried, tested, and proven. The result is seven chapters on key leadership qualities: creativity, competence, commitment, character, collegiality, compassion, and courage, and an appendix containing practical resources (discussion starters, diagrams, questionnaires, and the like) for developing leadership vision and goals within an organization.More specifically, as the title suggests, a main theme of the book is to invite readers to consider ways in which religious traditions can provide resources for cultivating not only excellent leaders but also “spirit-driven” leaders. For instance, in a chapter on commitment, Calian writes in direct reference to his own Christian tradition: “My working hypothesis in life is that sustainable and creative leadership is nurtured and maintained by a renewed awakening of faith, hope, and love in our everyday lives” (32–33). Indeed, Calian is set on making a case that great leadership must be “nurtured by our spiritual roots” (36). Consequently, such phrases as “people of faith in almost every religious tradition” (86), “the divine destiny envisioned” (88), or “religious standards in every tradition” (99) are sprinkled throughout the book.It is clear that for Calian great leadership is nurtured by religious traditions. Yet what is not so clear is how exactly this works. In other words, his general claims about religious traditions, life, and practices are often ambiguous and confusing. In fact, what Calian actually means by “spirit-driven” is simply not clear, but given its prominence in the title of the book, it should be. Perhaps one criticism of the book, then, is that its use of religious sources is too superficial to be insightful and thus helpful. [End Page 199]Todd V. CioffCalvin CollegeCopyright © 2013 Society of Christian Ethics... (shrink)

In August 2006, after twenty years of armed conflict, the Ugandan government and the rebel Lord’s Resistance Army came to a ceasefire agreement. While the LRA has moved its activity into neighboring countries, there has been peace—or at least the absence of overt conflict—in Uganda. The ecumenical Acholi Religious Leaders Peace Initiative (ARLPI) was critical in mediating between the two parties in the months leading up to the talks. Archbishop John Baptist Odama has been Chairperson of ARLPI since 2002. (...) Previous interviews with him have been short and focused on only his external actions—the negotiations with the LRA, the acts of solidarity with displaced people, children in particular. In the present interview, however, Archbishop Odama discusses the spiritual formation, the devotional practices, and the deep theology that inform his actions on behalf of peace and justice. (shrink)

The problem of how the brain produces consciousness, subjectivity and "something it is like to be" remains one of the greatest challenges to a complete science of the natural world. While various scientists and philosophers approach the problem from their own unique perspectives and in the terms of their own respective fields, Biophysics of Consciousness: A Foundational Approach attempts a consilience across disparate disciplines to explain how it is possible that an objective brain produces subjective experience. This volume unites the (...) cr me de la cr me of physicists, neuroscientists, and psychiatrists in the attempt to understand consciousness through a foundational approach encompassing ontological, evolutionary, neurobiological, and Freudian interpretations with the focus on conscious phenomena occurring in the brain. By integrating the perspectives of these diverse disciplines with the latest research and theories on the biophysics of the brain, the book tries to explain how what John Searle calls a "conscious field" can be an adaptive and causal element in the natural world. (shrink)

Creating a snapshot of current thinking about psychoanalysis, this lively collection examines the legacy of Freud and Lacan. Through provocative and penetrating arguments, the contributors take psychoanalysis to task for 0ts dark view of human nature, theoretical sorcery, devaluation of femininity, self-referentiality, discipleship, negativity, ignorance of history and more. The essays also examine the complex relationships between Freudian and Lacanian theory and philosophy, feminism, anthropology, communications theory, deconstruction, Foucauldian genealogy and medical history. The outstanding list of contributors includes Paul Roazen, (...) Francois Roustang, John Forrester, Rodolphe Gasche, Mikkel Borch-Jacobsen and Jacques Derrida. (shrink)

Think of the last thing someone did to you to seriously harm or offend you. And now imagine, so far as you can, becoming fully aware of the fact that his or her action was the causally inevitable result of a plan set into motion before he or she was ever even born, a plan that had no chance of failing. Should you continue to regard him or her as being morally responsible—blameworthy, in this case—for what he or she did? (...) Many have thought that, intuitively, you should not. Recently, Alfred Mele has employed this line of thought to mount what many have taken to be a powerful argument for incompatibilism: the “Zygote Argument”. However, in interesting new papers, John Martin Fischer and Stephen Kearns have each independently argued that the Zygote Argument fails. As I see it, the criticisms of Fischer and Kearns reveal some important questions about how the argument is meant to be—or how it would best be—understood. Once we make a slight (but important) modification to the argument, however, I think we will be able to see that the criticisms of Fischer and Kearns do not detract from its substantial force. (shrink)

The cognitivist/non-cognitivist debate about the nature and value of literary fiction has witnessed a lot of spilled ink amongst philosophers over the past decade. Gibson characterizes this debate as a conflict between two apparently incompatible intuitions: the ‘humanist’ intuition that works of literary fiction have some sort of cognitive value in telling us about the world, and the ‘sceptical’ anti-humanist intuition that such works, and their proper appreciation, are not essentially concerned with the notions of truth and knowledge. The vast (...) majority of recent writers on this issue have defended various versions of cognitivism, but the novelty of Gibson's cognitivist – or as he calls it ‘humanist’ – position consists in attempting to reconcile the two sides of the debate.Gibson thus takes seriously various sceptical arguments, primarily semantic and epistemological, to the effect that works of fiction qua fiction do not or cannot make reference to or represent the ‘real’ world and insofar as they do refer to it, they provide no evidence in themselves for forming justified beliefs about their claims. These arguments, Gibson holds, place a necessary ‘textual constraint’ on any plausible humanism, …. (shrink)